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bioorganic and medicinal chemistry impact factor 2020

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Help expand a public dataset of research that support the SDGs. Publish. Source Normalized Impact per Paper (SNIP). Careers - Terms and Conditions - Privacy Policy. Impact Factor: 2.572 ℹ Impact Factor: 2019: 2.572 The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 1993-2020: Scope: Bioorganic & Medicinal Chemistry publishes complete accounts of research of outstanding significance and timeliness on all aspects of molecular interactions at the interface of chemistry and biology, together with critical review articles. Go, Therapeutic peptides: Historical perspectives, current development trends, and future directions, Mapping pilicide anti-virulence effect in Escherichia coli, a comprehensive structure–activity study, Characterising covalent warhead reactivity, Polyketides from the marine-derived fungus Aspergillus falconensis: In silico and in vitro cytotoxicity studies, Discovery of 4-amino-1H-pyrazolo[3,4-d]pyrimidin derivatives as novel discoidin domain receptor 1 (DDR1) inhibitors, Design, synthesis and biological evaluation of novel thiazole-based derivatives as human Pin1 inhibitors, Recently reported biological activities of pyrazole compounds, Peptide therapeutics from venom: Current status and potential, An expedient process for reducing the formation of process-related impurities during solid-phase synthesis of potential nucleic acid-based drugs, Synthesis and structure-activity relationships for tetrahydroisoquinoline-based inhibitors of Mycobacterium tuberculosis, The splicing modulator sulfonamide indisulam reduces AR-V7 in prostate cancer cells, In support of equality, inclusion & diversity, Visibility. Throughout the year, the editors will select papers that present a real advance in the field, which will appear then in a dedicated “Editors’ Choice Collection”. Above all the presentation of a rational basis and a sound underlying hypothesis for the work is of particular importance, whatever its exact field. Discovery of novel pyrrole derivatives as potent agonists for the niacin receptor GPR109A, Development of 2-(4-pyridyl)-benzimidazoles as PKN2 chemical tools to probe cancer, Study on structure–activity relationship of vitamin K derivatives: Conversion of the naphthoquinone part into another aromatic ring and evaluation of their neuronal differentiation-inducing activity, Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitors, Structure-activity relationship of 4-azaindole-2-piperidine derivatives as agents against Trypanosoma cruzi, Synthesis of novel 4-Boc-piperidone chalcones and evaluation of their cytotoxic activity against highly-metastatic cancer cells, Potent bicyclic inhibitors of malarial cGMP-dependent protein kinase: approaches to combining improvements in cell potency, selectivity and structural novelty, Design, synthesis, bioactivity and mechanism of dithioacetal derivatives containing dioxyether moiety, Profiling interactions of vaborbactam with metallo-β-lactamases, Folic acid conjugates of a bleomycin mimic for selective targeting of folate receptor positive cancer cells, Utilizing comprehensive and mini-kinome panels to optimize the selectivity of quinoline inhibitors for cyclin G associated kinase (GAK), Modulation of mitochondrial dysfunction for treatment of disease, Peptides conjugated to 2-alkoxy-8-oxo-adenine as potential synthetic vaccines triggering TLR7, HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules, Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents, Improved radiosynthesis and preliminary in vivo evaluation of the 11C-labeled tetrazine [11C]AE-1 for pretargeted PET imaging, Discovery and lead optimisation of a potent, selective and orally bioavailable RARβ agonist for the potential treatment of nerve injury, Synthesis, biological evaluation and mode of action studies of novel amidinourea inhibitors of hepatitis C virus (HCV), Discovery of potent and selective 5-azaindazole inhibitors of leucine-rich repeat kinase 2 (LRRK2) – Part 1, Fluoromethylcyclopropylamine derivatives as potential in vivo toxicophores – A cautionary disclosure, Potent inhibitors of malarial P. Falciparum protein kinase G: Improving the cell activity of a series of imidazopyridines, Diversity-oriented synthesis of bicyclic fragments containing privileged azines, Discovery of heterocyclic replacements for the coumarin core of anti-tubercular FadD32 inhibitors, Quantitative structure–activity relationship analysis using deep learning based on a novel molecular image input technique, Discovery of super soft-drug modulators of sphingosine-1-phosphate receptor 1, Activating frataxin expression by single-stranded siRNAs targeting the GAA repeat expansion, A small diversity library of α-methyl amide analogs of sulindac for probing anticancer structure-activity relationships, Discovery of evocalcet, a next-generation calcium-sensing receptor agonist for the treatment of hyperparathyroidism, Synthesis and biological evaluation of aryl-oxadiazoles as inhibitors of Mycobacterium tuberculosis, A multi-gram-scale stereoselective synthesis of Z-endoxifen, Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II), New 4-aryl-1,3,2-oxathiazolylium-5-olates: Chemical synthesis and photochemical stability of a novel series of S-nitrosothiols, Novel SIRT1 activator MHY2233 improves glucose tolerance and reduces hepatic lipid accumulation in db/db mice, Activation loop targeting strategy for design of receptor-interacting protein kinase 2 (RIPK2) inhibitors, Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides, Identification of a 4-fluorobenzyl l-valinate amide benzoxaborole (AN11736) as a potential development candidate for the treatment of Animal African Trypanosomiasis (AAT), Repurposing Hsp90 inhibitors as antibiotics targeting histidine kinases, Synthesis and evaluation of analogues of the tuberculosis drug bedaquiline containing heterocyclic B-ring units, Synthesis and evaluation of 11C-labeled coumarin analog as an imaging probe for detecting monocarboxylate transporters expression, Synthesis of novel vitamin K derivatives with alkylated phenyl groups introduced at the ω-terminal side chain and evaluation of their neural differentiation activities, Diverse amide analogs of sulindac for cancer treatment and prevention, Elucidation of antimicrobial activity and mechanism of action by N-substituted carbazole derivatives, Antibiotic adjuvants – A strategy to unlock bacterial resistance to antibiotics, Validation of onchocerciasis biomarker N-acetyltyramine-O-glucuronide (NATOG), Download the ‘Understanding the Publishing Process’ PDF, Check the status of your submitted manuscript in the. Impact Factor: 2.572 ℹ Impact Factor: 2019: 2.572 The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. To calculate the five year Impact Factor, citations are counted in 2019 to the previous five years and divided by the source items published in the previous five years. Copyright © 2020 Elsevier Ltd. All rights reserved. To decline or learn more, visit our Cookies page. The journal publishes reports of experimental results in... Bioorganic & Medicinal Chemistry publishes complete accounts of research of outstanding significance and timeliness on all aspects of molecular interactions at the interface of chemistry and biology, together with critical review articles. Elsevier stands against racism and discrimination and fully supports the joint commitment for action in inclusion and diversity in publishing. Help expand a public dataset of research that support the SDGs. Help expand a public dataset of research that support the SDGs. The journal publishes reports of experimental results in medicinal chemistry, chemical biology and drug discovery and design, emphasizing new and emerging advances and concepts in these fields. In partnership with the communities we serve; we redouble our deep commitment to inclusion and diversity within our editorial, author and reviewer networks. Bioorganic & Medicinal Chemistry publishes complete accounts of research of outstanding significance and timeliness on all aspects of molecular interactions at the interface of chemistry and biology, together with critical review articles. Trust. Receive an update when the latest issues in this journal are published, https://doi.org/10.1016/S0968-0896(20)30179-6, https://doi.org/10.1016/j.bmc.2020.115343, https://doi.org/10.1016/j.bmc.2020.115344, Benny J. Evison, James T. Palmer, Gilles Lambert, Herbert Treutlein, ... James Bonnar, https://doi.org/10.1016/j.bmc.2020.115345, Bocheng Wu, Shaghayegh Fathi, Shanee Mortley, Mahir Mohiuddin, ... Adegboyega K. Oyelere, https://doi.org/10.1016/j.bmc.2020.115347, Teruyuki Tahara, Ami Watanabe, Maho Yutani, Yuko Yamano, ... Akira Iida, https://doi.org/10.1016/j.bmc.2020.115348, Katsushi Katayama, Yoshikazu Arai, Kenji Murata, Shoichi Saito, ... Tsuyoshi Muto, https://doi.org/10.1016/j.bmc.2020.115349, https://doi.org/10.1016/j.bmc.2020.115352, Jian Chen, Cheng Tao, Xiaofei Huang, Zide Chen, ... Zhengzhi Wu, https://doi.org/10.1016/j.bmc.2020.115353, Xiaoxue Chen, Yefang Zou, Jie Wang, Zhuoxian Cao, ... Bin He, https://doi.org/10.1016/j.bmc.2020.115354, Dezhong Ji, Wanwan Zhang, Yungen Xu, Jing-Jing Zhang, https://doi.org/10.1016/S0968-0896(20)30180-2, https://doi.org/10.1016/j.bmc.2020.115392, https://doi.org/10.1016/S0968-0896(20)30192-9, select article Discovery of disubstituted xylylene derivatives as small molecule direct inhibitors of Keap1-Nrf2 protein-protein interaction, Discovery of disubstituted xylylene derivatives as small molecule direct inhibitors of Keap1-Nrf2 protein-protein interaction, select article A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove, A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove, select article Pyrimethamine conjugated histone deacetylase inhibitors: Design, synthesis and evidence for triple negative breast cancer selective cytotoxicity, Pyrimethamine conjugated histone deacetylase inhibitors: Design, synthesis and evidence for triple negative breast cancer selective cytotoxicity, select article STAT3 inhibitory activity of naphthoquinones isolated from Tabebuia avellanedae, STAT3 inhibitory activity of naphthoquinones isolated from, select article Discovery and structure-activity relationships of spiroindolines as novel inducers of oligodendrocyte progenitor cell differentiation, Discovery and structure-activity relationships of spiroindolines as novel inducers of oligodendrocyte progenitor cell differentiation, select article An increase in side-group hydrophobicity largely improves the potency of ritonavir-like inhibitors of CYP3A4, An increase in side-group hydrophobicity largely improves the potency of ritonavir-like inhibitors of CYP3A4, select article CT2-3, a novel magnolol analogue suppresses NSCLC cells through triggering cell cycle arrest and apoptosis, CT2-3, a novel magnolol analogue suppresses NSCLC cells through triggering cell cycle arrest and apoptosis, select article Unexpected small molecules as novel SIRT2 suicide inhibitors, Unexpected small molecules as novel SIRT2 suicide inhibitors, select article Design, synthesis and biological evaluation of anthranilamide derivatives as potent SMO inhibitors, Design, synthesis and biological evaluation of anthranilamide derivatives as potent SMO inhibitors, select article Graphical Abstract Contents Continued.

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November 13, 2020 |

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